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Margot Vasseur

Application Engineer

Damae Medical

Biography

Margot is an Application Engineer at DAMAE Medical and has been actively involved in the development of the dermo-cosmetic division for the past two years. With a background in biotechnology engineering, she has developed strong expertise in LC-OCT image interpretation and in the extraction and analysis of quantitative skin biomarkers. Her work focuses on translating high-resolution 3D imaging data into meaningful insights to assess skin structure, function, and product efficacy for cosmetic and pharmaceutical research.

Conference

Day 2

Session 3: Hydration evaluation, what's new?

3D LC-OCT Skin Biomarkers for Evaluating Skin Hydration and Barrier Function

LC-OCT (Line-field Confocal Optical Coherence Tomography) enables non-invasive, real-time 3D imaging of the skin at cellular resolution. This cutting-edge technology provides detailed visualization of key skin structures, including the stratum corneum, epidermis, dermo-epidermal junction, dermal fibers, keratinocyte nuclei, and melanin. By capturing high-resolution images, LC-OCT offers unique insights into skin biology and mechanisms.

In the context of dermo-cosmetic research, LC-OCT enables precise evaluation of the effects of topical formulations on skin hydration and barrier integrity. When combined with advanced AI algorithms, it provides robust, quantitative, and reproducible metrics of skin microarchitecture and composition in vivo over time. These parameters serve as objective and reliable endpoints for product development and clinical studies, making LC-OCT a powerful tool for understanding skin physiology and evaluating the efficacy of hydration-focused cosmetic treatments

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